Brintellix (Vortioxetine)

Brintellix (Vortioxetine) is an antidepressant used to treat major depressive disorder (MDD) in adults. Vortioxetine is thought to work by increasing levels of serotonin in the brain, serotonin is a neurotransmitter. Vortioxetine’s mechanism of action (MOA) is thought to be related to the inhibition of the reuptake of serotonin (5-HT), it has other activities, including 5-HT3 receptor antagonism and 5-HT1A receptor agonism, but it is unclear whether these have an antidepressant effect. Vortioxetine is classified as a miscellaneous antidepressant, although some class vortioxetine it as a SSRI (selective serotonin reuptake inhibitor) or a serotonin modulator. The way it works is not completely understood. It is thought to work by affecting a natural chemical called serotonin in the brain.